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dronedarone will raise the amount or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Inappropriate behavior together with other adverse behavioral consequences are actually noted when utilizing benzodiazepines.
tecovirimat will enhance the degree or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep an eye on. Tecovirimat can be a weak inhibitor of CYP2C8 and CYP2C19. Observe for adverse effects if coadministered with sensitive substrates of these enzymes.
aprepitant will raise the stage or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
If Valium is always to be coupled with other psychotropic agents or anticonvulsant medications, thorough thought must be specified for the pharmacology of your agents for being employed - notably with regarded compounds which will potentiate the motion of diazepam, which include phenothiazines, narcotics, barbiturates, MAO inhibitors along with other antidepressants (see Drug Interactions).
nilotinib will enhance the amount or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
For individuals working with addressed far more regularly than encouraged, to reduce threat of withdrawal reactions, make use of a gradual taper to discontinue therapy (a client-distinct program need to be accustomed to taper the dose)
methylprednisolone will decrease the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
ethinylestradiol will enhance the level or result of diazepam by Mechanism: decreasing metabolism. Use Caution/Keep track of. Ethinyl estradiol may well inhibit the clearance of benzodiazepines that undergo oxidation, thus raising serum concentrations of concomitantly administered benzodiazepines.
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amobarbital will website lessen the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Reserve concomitant prescribing of these medication in sufferers for whom other treatment method alternatives are insufficient. Restrict dosages and durations to your minimum amount needed. Observe carefully for signs of respiratory melancholy and sedation.
lenacapavir will boost the stage or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.